Regenerative
Mesenchymal Stem Cell (MSC)-derived exosomes are tiny nanovesicles that act as the primary messengers for stem cell activity. They represent a revolution in regenerative therapy by delivering the repair and healing instructions of stem cells without using any living cells themselves.
These nanovesicles carry a potent, concentrated cargo of molecules—including specific growth factors, immunomodulatory proteins, and nucleic acids—that directly signal damaged cells to initiate a self-repair and regeneration program.
Musculoskeletal & Joint. Neurological & Systemic. Wound & Tissue Repair.
Key Regenerative Applications
MSC exosome therapy is highly valued for its ability to reduce inflammation, modulate immune response, and stimulate tissue repair in hard-to-reach areas.
Musculoskeletal | Joint Support
Musculoskeletal & Joint Support
Exosomes are widely utilized to target chronic joint pain and orthopedic injuries at the cellular level:
Osteoarthritis (OA): Injected directly into the joint space, exosomes reduce pain and inflammation by signaling chondrocytes (cartilage cells) to slow degradation and potentially promote repair.
Tendon & Ligament Repair: They deliver specific growth factors to injured tissues, accelerating the healing process of tears and chronic conditions like tendinopathy by promoting the formation of strong, organized collagen fibers.
Reduced Inflammation: Their core function is to dampen excessive inflammation in the joint capsule, which is the primary cause of pain and stiffness.
Neurological & Systemic
Neurological and Systemic Wellness
Due to their nano-size and natural composition, exosomes are uniquely positioned for systemic applications:
Crossing the Blood-Brain Barrier (BBB): Exosomes can naturally cross the BBB, offering a potential mechanism for delivering therapeutic cargo to the central nervous system for research into neurodegenerative conditions.
Systemic Anti-Inflammation: When administered intravenously, exosomes circulate throughout the body, providing broad immune modulation and systemic reduction of chronic inflammation associated with various systemic conditions.
Wound & Tissue Repair
Wound and Tissue Repair
MSC Exosomes are crucial mediators in complex wound and tissue repair because they orchestrate a successful healing response, moving beyond simple closure to achieve high-quality tissue regeneration.
Anti-Inflammatory Control: Exosomes rapidly deliver potent anti-inflammatory proteins to the injury site, which is crucial for preventing the excessive, prolonged inflammation that leads to chronic wounds and thick scars.
Healing Acceleration: They stimulate the growth and migration of surrounding skin cells (keratinocytes and fibroblasts), speeding up wound closure and regeneration.
Quality Tissue Remodeling: Exosomes guide fibroblasts to lay down organized, high-quality tissue rather than disorganized scar tissue. They promote angiogenesis (new blood vessel formation) to ensure the healed tissue is strong, well-nourished, and aesthetically optimized.
Heal. Restore. Renew.
Easy Delivery Methods
We've created two fantastic methodologies for receiving exosome treatments, offering flexibility and targeted results. We deliver the powerful regenerative potential of exosomes through both topical application for focused skin and hair restoration, and a precise injection method designed for deeper, longer-lasting cellular revitalization.
Direct & Potent Cellular Treatment
Sterile Saline MSC Exosomes
For the most direct and potent cellular treatment, the precise injection method delivers a highly concentrated dose of exosomes straight to the target area—whether that's the deeper layers of the skin, the scalp for hair restoration, or localized areas of concern. This ensures the exosomes' powerful cargo of growth factors and signaling molecules immediately begins the work of cellular communication, deep tissue repair, and targeted regeneration, promoting more profound and lasting results.
Non-Invasive, Easy Application
Topical Method
For those seeking non-invasive and easy application, our topical method allows for the powerful benefits of exosomes to be gently absorbed. By delivering the concentrated regenerative factors directly onto the skin or scalp's surface, this method supports surface-level rejuvenation, enhances skin texture, reduces inflammation, and encourages a healthier healing environment without the need for needles. It’s the perfect way to incorporate cutting-edge cell-free therapy into your daily routine.
Why Exosomes Over Other Regenerative Treatments?
Why Choose Exosomes
Exosomes represent a significant leap forward in regenerative aesthetics, offering the potent signaling power of stem cells without the use of any living cells. This allows for a superior, safer, and often more efficient alternative to older technologies like cellular therapies or traditional blood products.
Cell-Free Safety
Exosomes carry no cellular DNA, eliminating the risk of immune rejection or unwanted cell growth (unlike whole stem cells).
High Potency & Stability
They carry a highly concentrated, synergistic payload of regenerative factors far surpassing traditional treatments like Platelet-Rich Plasma (PRP).
Minimal Downtime
Because they accelerate the body's natural healing pathways, treatments typically involve less redness and recovery time than standalone procedures.
FAQs
Frequently Asked Questions
Q: What is the fundamental difference between syringe - based and topical exosome treatments?
Syringe-Based (Injected): This method targets specific, deeper tissues (like joints, tendons, or the scalp) or uses intravenous (IV) delivery for systemic, whole-body benefits. It allows for a higher concentration of exosomes to be delivered directly to the site of damage, promoting regeneration and reducing deep inflammation.
Topical (Surface Applied): This method is typically used for aesthetic purposes (skin rejuvenation, anti-aging, scarring). The exosomes are applied to the skin's surface, often following a procedure like micro needling or laser treatment, to enhance skin repair, boost collagen production, and reduce surface inflammation.
Q: What conditions are best suited for each delivery method?
Injected Exosomes: Primarily used for musculoskeletal issues (e.g., osteoarthritis, tendonitis, ligament tears), chronic systemic inflammation, certain neurological support, and deeper applications like hair restoration (injected into the scalp).
Topical Exosomes: Primarily used for surface issues like fine lines, wrinkles, acne scars, hyperpigmentation, and general skin texture and tone improvement. They leverage the exosomes' cargo to stimulate localized cellular turnover and repair.
Q: How quickly can I expect to see results, and how long do they last?
Initial Results: With topical applications, patients often notice a "glow" and improved hydration within days, with true regenerative results appearing in 4–6 weeks. For injected treatments, functional improvement (like reduced joint pain) typically begins in 4–8 weeks, peaking at 3 to 6 months.
Longevity: Because exosomes initiate a natural regenerative process, the effects are long-lasting, often sustained for 6 to 18 months or more, depending on the treated condition, the individual's overall health, and lifestyle factors. Maintenance treatments may be recommended.
Q: Are MSC exosomes safe, and what are the potential side effects?
Safety: MSC-derived exosomes are generally considered a low-risk, cell-free therapy. Unlike whole stem cells, they cannot replicate or differentiate, eliminating the risk of tumor formation or immune rejection.
Side Effects:
Injected: Minor, temporary side effects may include localized pain, swelling, redness, or bruising at the injection site, similar to any injection.
Topical: Minor side effects are usually limited to mild, temporary redness or tingling, particularly when combined with micro needling.
Q: Are Exosome treatments FDA approved?
Currently, no exosome product is fully approved by the U.S. Food and Drug Administration (FDA) for the general treatment of specific diseases or for broad cosmetic use.
The FDA classifies exosomes derived from human tissue as biological drug products and is actively regulating them. Many clinics offer these treatments under the legal practice of medicine and science based on ongoing research and clinical experience, but patients should be aware that they are not yet fully FDA-approved commercial products.
6. Do I need to receive a series of treatments, or is one session enough?
While a single injected treatment can offer noticeable relief, a series of treatments (typically 2–4 sessions) spaced several weeks apart is often recommended to maximize and sustain the regenerative effects, particularly for chronic conditions or significant aesthetic goals (like severe hair loss or scarring). The exact protocol depends entirely on the specific application and the patient's individual response.
At B&H BIO, We've created two fantastic methodologies for receiving exosome treatments, offering flexibility and targeted results. We deliver the powerful regenerative potential of exosomes through both topical application for focused skin and hair restoration, and a precise injection method designed for deeper, longer-lasting cellular revitalization.
Pages
© 2025 B&H BIO - All Rights Reserved. Powered By NuBrand Ai
DISCLAIMER
This website is provided for informational purposes only. The content on this website is not intended to offer clinical treatment or medical advice. It is not a substitute for professional medical guidance, diagnosis, or treatment.
We Do Not Sell to Patients
Please note that this website does not facilitate the sale of products directly to patients. While we may provide information about our products, they are not intended or sold as clinical treatments. If you require medical treatment or have medical concerns, we strongly recommend consulting with a qualified healthcare professional for appropriate guidance.
Not Sold as a Clinical Treatment
The products featured on this website are not marketed, sold, or intended for use as clinical treatments for any medical condition. They may have wellness or lifestyle applications, but they are not substitutes for approved clinical therapies.The information provided on this website is subject to change without notice, and we make no warranties or representations about the accuracy, completeness, or timeliness of the information presented. By using this website, you acknowledge and agree to the terms and conditions of this disclaimer. If you do not agree with these terms, please refrain from using this website. For any questions or concerns related to the content or information on this website, please contact us using the provided contact details.
Regulatory Notice Regarding Exosome Products
It's crucial to understand the current regulatory status of these products:
These exosome products are intended solely for investigative research purposes and are not approved by the FDA (U.S. Food and Drug Administration) for use as treatments or therapies.
Patients and healthcare providers must exercise extreme caution. Before considering the use of stem cell-derived exosomes for any medical condition, you should thoroughly consult with regulatory authorities and experts. Do not use these products outside of a properly authorized clinical trial.